This is a SAS(r) Software macro package for performing multipoint QTL mapping using the DeFries-Fulker multiple regression approach to unselected and selected samples.
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1.00Added citation footnote. 0.10Added the Sham-Purcell modification of the Haseman-Elston model Double entry is not used for the Haseman-Elston basic and the Sham-Purcell model even if the data is double entered. This allows direct comparison of the DF, HE, and SP models from the same run. Set p to 1.0 for values of t from the wrong tail 0.09 Fix a bug that allowed individuals with missing phenotypes to be counted in the regressions. Updated the required citation in the documentation and license to be "in press" in Bioinformatics, instead of just a web citation. 0.08Documentation update. 0.07 Change as-is option to asis, and make it actually work. Include NOTES, ChangeLog, and How-To in distribution. Fix outdata bug and missing value bug. 0.06 The DF Augmented model now reports the t of interaction term. The beta of the interaction term is also reported. 0.05 The New Haseman-Elston model has been added. This model is (sib1 - mean(sib1))*(sib2 - mean(sib2)) = pihat. A typo that caused a bias in t was fixed. 0.04 This releases fixes a bug with the model degrees of freedom. Model DF now reflects the number of independent variables in the regression, which lets the script correctly compute the fit statistics for each model. 0.03 Completed features desired for first full release. Added plotting options to macro call. Added influence statistics. Added DeFries-Fulker Augmented model.
0.10Added the Sham-Purcell modification of the Haseman-Elston model Double entry is not used for the Haseman-Elston basic and the Sham-Purcell model even if the data is double entered. This allows direct comparison of the DF, HE, and SP models from the same run. Set p to 1.0 for values of t from the wrong tail 0.09 Fix a bug that allowed individuals with missing phenotypes to be counted in the regressions. Updated the required citation in the documentation and license to be "in press" in Bioinformatics, instead of just a web citation. 0.08Documentation update. 0.07 Change as-is option to asis, and make it actually work. Include NOTES, ChangeLog, and How-To in distribution. Fix outdata bug and missing value bug. 0.06 The DF Augmented model now reports the t of interaction term. The beta of the interaction term is also reported. 0.05 The New Haseman-Elston model has been added. This model is (sib1 - mean(sib1))*(sib2 - mean(sib2)) = pihat. A typo that caused a bias in t was fixed. 0.04 This releases fixes a bug with the model degrees of freedom. Model DF now reflects the number of independent variables in the regression, which lets the script correctly compute the fit statistics for each model. 0.03 Completed features desired for first full release. Added plotting options to macro call. Added influence statistics. Added DeFries-Fulker Augmented model.
0.09 Fix a bug that allowed individuals with missing phenotypes to be counted in the regressions. Updated the required citation in the documentation and license to be "in press" in Bioinformatics, instead of just a web citation. 0.08Documentation update. 0.07 Change as-is option to asis, and make it actually work. Include NOTES, ChangeLog, and How-To in distribution. Fix outdata bug and missing value bug. 0.06 The DF Augmented model now reports the t of interaction term. The beta of the interaction term is also reported. 0.05 The New Haseman-Elston model has been added. This model is (sib1 - mean(sib1))*(sib2 - mean(sib2)) = pihat. A typo that caused a bias in t was fixed. 0.04 This releases fixes a bug with the model degrees of freedom. Model DF now reflects the number of independent variables in the regression, which lets the script correctly compute the fit statistics for each model. 0.03 Completed features desired for first full release. Added plotting options to macro call. Added influence statistics. Added DeFries-Fulker Augmented model.
0.08 Documentation update. 0.07 Change as-is option to asis, and make it actually work. Include NOTES, ChangeLog, and How-To in distribution. Fix outdata bug and missing value bug. 0.06 The DF Augmented model now reports the t of interaction term. The beta of the interaction term is also reported. 0.05 The New Haseman-Elston model has been added. This model is (sib1 - mean(sib1))*(sib2 - mean(sib2)) = pihat. A typo that caused a bias in t was fixed. 0.04 This releases fixes a bug with the model degrees of freedom. Model DF now reflects the number of independent variables in the regression, which lets the script correctly compute the fit statistics for each model. 0.03 Completed features desired for first full release. Added plotting options to macro call. Added influence statistics. Added DeFries-Fulker Augmented model.
0.07 Change as-is option to asis, and make it actually work. Include NOTES, ChangeLog, and How-To in distribution. Fix outdata bug and missing value bug. 0.06 The DF Augmented model now reports the t of interaction term. The beta of the interaction term is also reported. 0.05 The New Haseman-Elston model has been added. This model is (sib1 - mean(sib1))*(sib2 - mean(sib2)) = pihat. A typo that caused a bias in t was fixed. 0.04 This releases fixes a bug with the model degrees of freedom. Model DF now reflects the number of independent variables in the regression, which lets the script correctly compute the fit statistics for each model. 0.03 Completed features desired for first full release. Added plotting options to macro call. Added influence statistics. Added DeFries-Fulker Augmented model.
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