Identification and scoring of cancer markers by Immunohistochemistry has been shown to be of value in determining the aggressiveness of specific cancers, as well as in predicting patient outcome for many cancer types. Despite its routine clinical use, a problem with the standard scoring method is the inherent subjectivity and variability of purely visual inspection. To diminish this visual perception biasing, IHC profiler has been developed as a standard automated scoring tool.
Full Publication and Citation: Varghese F, Bukhari AB, Malhotra R, De A (2014) IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples. PLoS ONE 9(5): e96801. doi:10.1371/journal.pone.0096801
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- Automated immunohistochemistry (IHC) image analysis
- Easy to use
- Bias free analysis
- Open source plugin compatible with ImageJ
- Fast analysis
Excellent project.. Helped me a lot through my IHC analysis..
IHC profiler is a very handy tool that made my IHC analysis easier than expected.