Bison allows users with access to a computer cluster to rapidly align whole-genome bisulfite sequencing or RRBS reads. It can align both directional and non-directional libraries and uses bowtie2.
Multiple compute nodes are not absolutely required, but will make the alignment process faster.
Further details available on the Wiki page. Help also available on SEQanswers (http://seqanswers.com/forums/showthread.php?t=31314) or by creating a ticket here.
You can now track the development on github (https://github.com/dpryan79/bison).
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