Seal is a Hadoop-based distributed short read alignment and analysis toolkit. Currently Seal includes tools for: read demultiplexing, read alignment, duplicate read removal, sorting read mappings, and calculating statistics for empirical base quality recalibration. Seal scales, easily handling TB of data.
- short read alignment (based on BWA)
- duplicate read identification
- sort read mappings
- calculate empirical base quality recalibration tables
- fast, scalable, reliable (runs on Hadoop)
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