Census

File Release Notes and Changelog

Release Name: Census 1.0b1

Notes:
CENSUS RELEASE NOTES
--------------------
v. 1.0b1 (04/10/2006)
Justin Wilkins (justin.wilkins@farmbio.uu.se)

http://census.sourceforge.net

NONMEM is an extremely powerful tool for nonlinear mixed-effect modelling and simulation of pharmacokinetic and pharmacodynamic data. However, it is a console-based application whose output does not lend itself to rapid interpretation or efficient management. Census has been created to be a comprehensive project manager for NONMEM, providing detailed summary, comparison and overview of the runs comprising a given project, including the display of output data, simple post-run processing, fast diagnostic plots and run output management, complementary to other available modelling aids. Analysis time ought not to be spent on trivial tasks, and Census's role is to eliminate these as far as possible by increasing the efficiency of the modelling process. 

Census is made available under the Mozilla Public License, version 1.1.

INSTALLATION
------------

Execute the Windows setup file and installation will proceed automatically.

COMPILING
---------

You will need:

Borland Developer Studio (BDS) 2006 Professional (or better), with the Delphi for Win32 personality active. 

Additional tools:

R-(D)COM (link library for R under Win32)	http://cran.r-project.org/contrib/extra/dcom/

Optional:

Inno Setup (for compiling installer)		http://www.innosetup.com/
ISTool (frontend for Inno Setup)		http://www.istool.org/
UPX (Executable packer)				http://upx.sourceforge.net/

You will also need the following Delphi components:

FlashFiler 						http://sourceforge.net/projects/tpflashfiler/		
Orpheus 						http://sourceforge.net/projects/tporpheus/			
JEDI Visual Component Library (JVCL+JCL) 		http://jvcl.sourceforge.net/	
VirtualTreeView						http://www.soft-gems.net/VirtualTreeview/
TBrkApart 						http://www.delphi32.com/vcl/3359/
XPMenu 							http://www.shagrouni.com/english/software/xpmenu.html
KStringGrid						http://www.korzh.com/delphi/components/
SysTools 						http://sourceforge.net/projects/tpsystools/	
ZipMaster						http://www.geocities.com/rjpeters_au/zipmaster.html	
Compile Time Expert 					http://www.geocities.com/SiliconValley/Hills/1335/
TdfsMRUFileList						http://www.delphifreestuff.com/
AAstrms							http://www.thedelphimagazine.com/samples/1248/article.htm
DMath							http://www.unilim.fr/pages_perso/jean.debord/tpmath/tpmath.htm
FastHTMLParser						http://www.jazarsoft.com/main.php
KProcs & KCtls						http://www.korzh.com/delphi
TPerlRegEx						http://www.regular-expressions.info/delphi.html
RDelphi							http://www.menne-biomed.de/download/download.html
SynEdit							http://synedit.sourceforge.net/
VKReports						http://vlad-karpov.narod.ru/Components.html
ZeusDBO & ZeosControls					http://www.zeoslib.org

If you find any dependencies not included here, please let me know. As a rule of thumb, they may (in fact, should) be discarded. If any of these components are unavailable, please let me know and I'll make them available.

To generate an executable, install all the above components into the BDS IDE, load Census.bdsproj, and compile. Of course, this will never work first time out of the gate, but once all the components are on board and working happily with one another, things should be all right.

ACKNOWLEDGMENTS 
---------------

Special thanks go to Kristin Carlsson, Lena Friberg, Nick Holford, Andrew Hooker, Niclas Jonsson, Mats Karlsson, Grant Langdon, Lars Lindbom, Helen McIlleron, Pontus Pihlgren, Colin Pillai, Angelica Quartino, Pete Smith, and Janet Wade for (variously) ideas, testing, and support.

UPDATES
-------

The most recent version of the source will always be available from http://census.sourceforge.net/.

KNOWN ISSUES
------------

* Using trees is not 100% stable. Handle with care.





Changes:
CENSUS CHANGELOG
----------------
Justin Wilkins (justin.wilkins@farmbio.uu.se)

22/11/2005 (0.998r4)
----------

* First public release of source.

19/01/2006 (0.998r5)
----------

* ADDED: Support for $OMEGA and $SIGMA records in the PRIOR functionality of NONMEM VI.
* ADDED: Splash screen.
* ADDED: Checks for R, R-(D)COM and Xpose. If all three are detected, the libraries are 
    loaded. If not, a warning dialog is displayed.
* FIXED: Crash using the 'Package runs' option. ZipMaster DLL updated to v1.78.9.5. Added 
    logic to check DLL version automatically, reported in About dialog.
* UPDATED: R(D)COM server, to 2.01.

20/01/2006 (0.998r5a)
----------

* FIXED: Nasty crash on startup, caused by a dodgy component. Removed ZipMaster DLL checks,
    new DLL installed by default at runtime.

04/10/2006 (1.0b1)
----------
* ADDED: Xpose integration underway; Xpose plots are now the default graphing option in Census (R version 2.2.1 or better, Xpose 4.0 RC3 update 7 or better, and R-(D)COM 2.0 or better - supplied)
* ADDED: New icons
* ADDED: New data display mode: parameter comparisons
* ADDED: Warning messages are now included in the main window display
* ADDED: Notes are now captured from NONMEM control streams - any line beginning with ';;;' is now considered to be a Note
* ADDED: The main display window has been adjusted to allow the introduction of branching trees (to follow in a later release)
* ADDED: Many, many more