I'm new to Spyce, but not to PSP. I would advise keeping away from ASP
Python pages, it's easy to get into strange bugs that are buried in the
MS murk. I used the Webware PSP implementation with IIS. It works
fine, although the install is a little complicated ( you have to use
py2exe to create an .exe from the cgi ). The whole Webware thing is
more complicated ( with application contexts and appservers ) but you
might want those features. Anyway I haven't used Sypce with IIS so
can't speak to that, but I like what I have seen so far..