Reporting a situation that arose with my first Python applet, while prepping a test distribution for Win98 -- seems that py2exe will build fine with either the Unicode or ANSI version of wxPython, but the resulting .exe throws a page fault if the Unicode version is used:
 
MyApplet caused an invalid page fault in
module MSVCR71.DLL at 0167:7c34a17c.
 
Using the ANSI wxPython version produces a working .exe. This fix was provided by researching this mailing list -- great resource! I tried a number of other published fixes before switching to ANSI wxPython, but got the same error.
 
However, being somewhat a novice, I need to know what are the consequences of using the ANSI version for an international distribution, where I'd expect to run into extensive Unicode usage?