#1725 trunk neural crest cell migration

None
closed-accepted
Cynthia Smith
5
2014-05-06
2014-03-18
No

Please add:

abnormal trunk neural crest cell migration
DEF: any anomaly in the migratory path or behavior of the neural crest cells (NCCs) that arise from the trunk neural crest which lies between the vagal and sacral neural crest; there are two major pathways taken by the migrating trunk NCCs: (1) one group of cells fated to become melanocytes (the melanin-forming pigment cells) migrates dorsolaterally into the ectoderm towards the ventral midline and colonizes the skin and hair follicles; (2) a second group of cells migrates ventrolaterally through the anterior portion of each sclerotome; the cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons, whereas those that continue more ventrally form the sympathetic ganglia, chromaffin cells of the adrenal medulla, Schwann (precursor) cells, and the nerve clusters surrounding the aorta
SYN: abnormal body neural crest cell migration
SYN: abnormal body NCC migration
SYN: abnormal trunk NCC migration
SYN: abnormal truncal neural crest cell migration
SYN: abnormal truncal NCC migration
From J:143845

SOURCES:

(1) The Neural Crest http://www.ncbi.nlm.nih.gov/books/NBK10065/

(2) Wikipedia http://en.wikipedia.org/wiki/Truncal_neural_crest

NOTE: According to the LifeMap Discovery site (http://discovery.lifemapsc.com/in-vivo-development/neural-crest/trunk-neural-crest/trunk-neural-crest-cells) and diagrams shown in http://www.d.umn.edu/~pschoff/documents/NeuralCrest_000.pdf, trunk neural crest cells span from somite 5 (S5) to the caudal tip of the neural tube

Thanks

Anna

Discussion

  • Cynthia Smith
    Cynthia Smith
    2014-05-06

    • status: open --> closed-rejected
    • assigned_to: Cynthia Smith
    • Group: -->
     
  • Cynthia Smith
    Cynthia Smith
    2014-05-06

    abnormal trunk neural crest cell migration MP_0013012

     
  • Cynthia Smith
    Cynthia Smith
    2014-05-06

    • status: closed-rejected --> closed-accepted