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[Obo-phenotype-commits] obo/ontology/phenotype mammalian_phenotype.obo, 1.431, 1.432 mosquito_insecticide_resistance.obo, 1.1196, 1.1197
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From: Seth C. <sjc...@us...> - 2011-09-15 07:02:05
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Update of /cvsroot/obo/obo/ontology/phenotype In directory vz-cvs-4.sog:/tmp/cvs-serv17715/phenotype Modified Files: mammalian_phenotype.obo mosquito_insecticide_resistance.obo Log Message: Automated file update Index: mammalian_phenotype.obo =================================================================== RCS file: /cvsroot/obo/obo/ontology/phenotype/mammalian_phenotype.obo,v retrieving revision 1.431 retrieving revision 1.432 diff -C2 -d -r1.431 -r1.432 *** mammalian_phenotype.obo 1 Sep 2011 07:02:18 -0000 1.431 --- mammalian_phenotype.obo 15 Sep 2011 07:02:02 -0000 1.432 *************** *** 1,4 **** format-version: 1.2 ! date: 27:07:2011 16:12 saved-by: csmith auto-generated-by: OBO-Edit 2.0 --- 1,4 ---- format-version: 1.2 ! date: 13:09:2011 14:33 saved-by: csmith auto-generated-by: OBO-Edit 2.0 *************** *** 661,667 **** id: MP:0000111 name: cleft palate - alt_id: MP:0000429 alt_id: Argent:4876 def: "congenital fissure of the tissues normally uniting to form the palate" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", PMID:9753320] synonym: "palatoschisis" EXACT [] is_a: MP:0003755 ! abnormal palate morphology --- 661,668 ---- id: MP:0000111 name: cleft palate alt_id: Argent:4876 + alt_id: MP:0000429 def: "congenital fissure of the tissues normally uniting to form the palate" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", PMID:9753320] + subset: CvDC_Terms synonym: "palatoschisis" EXACT [] is_a: MP:0003755 ! abnormal palate morphology *************** *** 1744,1747 **** --- 1745,1749 ---- id: MP:0000284 name: double outlet heart right ventricle + alt_id: Argent:600 alt_id: MP:0000283 def: "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", J:67826] *************** *** 1843,1846 **** --- 1845,1849 ---- id: MP:0000297 name: abnormal atrioventricular cushion morphology + alt_id: Argent:1100 def: "any structural anomaly of the mounds of embryonic connective tissue that bulge into the fetal atrioventricular canal; these mounds eventually fuse to form the valves between the right and left atrioventricular orifices and the atrioventricular septum" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"] subset: CvDC_Terms *************** *** 3308,3312 **** --- 3311,3317 ---- id: MP:0000519 name: hydronephrosis + alt_id: Argent:4502 def: "dilation of the pelvis and calices of one or both kidneys" [J:56641] + subset: CvDC_Terms synonym: "hydropic kidney" EXACT [] synonym: "renal pelvic dilation" EXACT [] *************** *** 3635,3639 **** --- 3640,3646 ---- id: MP:0000562 name: polydactyly + alt_id: Argent:4103 def: "greater than the normal complement of digits on one or more autopods" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"] + subset: CvDC_Terms subset: Europhenome_Terms synonym: "extra fingers" NARROW [] *************** *** 4194,4198 **** --- 4201,4207 ---- id: MP:0000644 name: dextrocardia + alt_id: Argent:110 def: "congenital defect in which the heart is located on the right side of the thorax instead of on the left side (levocardia, the normal position)" [MESH:C14.240.400.280, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + subset: CvDC_Terms is_a: MP:0006065 ! abnormal heart position or orientation *************** *** 6078,6081 **** --- 6087,6091 ---- synonym: "open anterior neuropore" EXACT [] is_a: MP:0003720 ! abnormal neural tube closure + is_a: MP:0011259 ! abnormal cephalic neural fold morphology [Term] *************** *** 13871,13878 **** id: MP:0002135 name: abnormal kidney morphology alt_id: MP:0000518 alt_id: MP:0003650 - alt_id: Argent:4512 def: "any structural anomaly of either of the two excretory organs that filter wastes (especially urea) from the blood and excrete them and water in urine" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] synonym: "abnormal renal morphology" EXACT [] synonym: "kidney dysplasia" EXACT [] --- 13881,13889 ---- id: MP:0002135 name: abnormal kidney morphology + alt_id: Argent:4512 alt_id: MP:0000518 alt_id: MP:0003650 def: "any structural anomaly of either of the two excretory organs that filter wastes (especially urea) from the blood and excrete them and water in urine" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + subset: CvDC_Terms synonym: "abnormal renal morphology" EXACT [] synonym: "kidney dysplasia" EXACT [] *************** *** 17518,17522 **** --- 17529,17535 ---- id: MP:0002633 name: persistent truncus arteriosis + alt_id: Argent:500 def: "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:pvb "Pierre Vanden Borre, Mouse Genome Informatics Curator"] + subset: CvDC_Terms synonym: "common arterial trunk" EXACT [] synonym: "persistent truncus arteriosus" EXACT [] *************** *** 17568,17572 **** --- 17581,17587 ---- id: MP:0002639 name: micrognathia + alt_id: Argent:4163 def: "abnormally reduced size of the jaws, especially of the mandible" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:pvb "Pierre Vanden Borre, Mouse Genome Informatics Curator"] + subset: CvDC_Terms synonym: "brachygnathia" NARROW [] synonym: "brachygnathism" NARROW [] *************** *** 18543,18548 **** --- 18558,18565 ---- name: situs inversus def: "lateral transposition or mirroring of the viscera of the thorax and abdomen, sometimes incomplete, with all organs maintaining the normal relative position with respect to each other" [MESH:C16.131.810, PMID:16461029] + subset: CvDC_Terms synonym: "situs inversus viscerum" EXACT [] synonym: "visceral inversion" EXACT [] + xref: MPATH:720 is_a: MP:0004133 ! heterotaxia *************** *** 18550,18555 **** id: MP:0002767 name: situs ambiguus ! def: "failure of asymmetry of unpaired organs and/or a condition where at least one organ shows a reversed orientation along the left-right axis, such as in the heart, liver, spleen, stomach, small bowl and colon" [PMID:16461029] synonym: "situs ambiguous" RELATED [] is_a: MP:0004133 ! heterotaxia --- 18567,18574 ---- id: MP:0002767 name: situs ambiguus ! def: "an abnormality in which the thoracic and abdominal organs are positioned in such a way with respect to each other and the left-right axis as to be not clearly lateralised and thus have neither the usual, or normal (situs solitus), nor the mirror-imaged (situs inversus) arrangements" [PMID:18039396] ! subset: CvDC_Terms synonym: "situs ambiguous" RELATED [] + xref: MPATH:711 is_a: MP:0004133 ! heterotaxia *************** *** 19862,19866 **** id: MP:0002950 name: abnormal neural crest cell migration ! def: "defect in the dispersion of the transient and migratory group of cells that emerge from the dorsal region of the neural tube and migrate to many peripheral locations to form various tissues of the adult" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"] synonym: "abnormal NCC migration" EXACT [] is_a: MP:0008932 ! abnormal embryonic tissue physiology --- 19881,19885 ---- id: MP:0002950 name: abnormal neural crest cell migration ! def: "any anomaly in the dispersion of the transient and migratory group of cells that emerge from the dorsal region of the neural tube and migrate to many peripheral locations to form various tissues of the adult" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"] synonym: "abnormal NCC migration" EXACT [] is_a: MP:0008932 ! abnormal embryonic tissue physiology *************** *** 20084,20088 **** id: MP:0002982 name: abnormal primordial germ cell migration ! def: "defects in the orderly movement of a primordial germ cell, a cell specialized to produce haploid gametes, from one site to another during development" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] synonym: "abnormal germ cell migration" RELATED [] synonym: "abnormal PGC migration" EXACT [] --- 20103,20107 ---- id: MP:0002982 name: abnormal primordial germ cell migration ! def: "any anomaly in the orderly movement of a primordial germ cell, a cell specialized to produce haploid gametes, from one site to another during development" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] synonym: "abnormal germ cell migration" RELATED [] synonym: "abnormal PGC migration" EXACT [] *************** *** 20809,20813 **** id: MP:0003091 name: abnormal cell migration ! def: "defect in the movement of cells during developmental or chemotactic processes" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] is_a: MP:0005621 ! abnormal cell physiology --- 20828,20832 ---- id: MP:0003091 name: abnormal cell migration ! def: "any anomaly in the movement of cells from one site to another, often occuring during developmental or chemotactic processes" [GO:0016477, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0005621 ! abnormal cell physiology *************** *** 25888,25892 **** synonym: "abnormal Muller duct morphology" EXACT [] synonym: "abnormal paramesonephric duct" EXACT [] - is_a: MP:0003936 ! abnormal reproductive system development is_a: MP:0008487 ! abnormal mesonephros morphology --- 25907,25910 ---- *************** *** 25900,25904 **** synonym: "abnormal mesonephric duct" EXACT [] synonym: "abnormal nephric duct" EXACT [] - is_a: MP:0003936 ! abnormal reproductive system development is_a: MP:0008487 ! abnormal mesonephros morphology --- 25918,25921 ---- *************** *** 27456,27459 **** --- 27473,27477 ---- def: "any structural anomaly of the mesenchymal cells that give rise to the corneal endothelium, corneal stroma, sclera, iris stroma, ciliary muscle, ciliary stroma, and trabecular meshwork of the eye" [J:102847, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] is_a: MP:0001286 ! abnormal eye development + is_a: MP:0011260 ! abnormal head mesenchyme morphology [Term] *************** *** 27892,27895 **** --- 27910,27914 ---- id: MP:0004113 name: abnormal aortic arch morphology + alt_id: Argent:2700 def: "any structural anomaly of the convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"] comment: Note that this term refers to the adult aortic arch structure. For multiple aortic arches present in the embryo, see the term for embryonic aortic arches [abnormal branchial arch artery morphology; MP:0002672]. *************** *** 28055,28062 **** --- 28074,28084 ---- id: MP:0004133 name: heterotaxia + alt_id: Argent:190 def: "abnormal arrangement of organs or parts of the body in relation to each other according to the left-right axis" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", PMID:16461029] + subset: CvDC_Terms synonym: "abnormal bilateral symmetry" EXACT [] synonym: "heterotaxis" EXACT [] synonym: "heterotaxy" EXACT [] + xref: MPATH:712 is_a: MP:0005378 ! growth/size phenotype *************** *** 28233,28236 **** --- 28255,28259 ---- id: MP:0004158 name: right aortic arch + alt_id: Argent:2720 def: "the aortic arch lies to the right of the trachea and esophagus; results from persistence of the entire right dorsal arch and involution of a segment of the left arch" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] subset: CvDC_Terms *************** *** 28613,28618 **** [Term] id: MP:0004213 ! name: abnormal unami taste sensitivity ! def: "changes in the ability to perceive a particular flavor or suggestion of something unami (savory) by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0001986 ! abnormal taste sensitivity --- 28636,28641 ---- [Term] id: MP:0004213 ! name: abnormal umami taste sensitivity ! def: "changes in the ability to perceive a particular flavor or suggestion of something umami (savory) by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0001986 ! abnormal taste sensitivity *************** *** 32352,32356 **** --- 32375,32381 ---- id: MP:0004733 name: abnormal thoracic cavity + alt_id: Argent:4907 def: "any structural anomaly of the cavity in the vertebrate body enclosed by the ribcage between the diaphragm and the neck, and contains the lungs, heart, thoracic aorta, pulmonary artery and its branches, thymus gland, and the respiratory airway" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + subset: CvDC_Terms synonym: "abnormal rib cavity" EXACT [] is_a: MP:0004134 ! abnormal chest morphology *************** *** 33159,33163 **** def: "any anomaly in the process by which the edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] synonym: "abnormal neural groove formation" EXACT [] ! is_a: MP:0003861 ! abnormal nervous system development [Term] --- 33184,33188 ---- def: "any anomaly in the process by which the edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] synonym: "abnormal neural groove formation" EXACT [] ! is_a: MP:0008932 ! abnormal embryonic tissue physiology [Term] *************** *** 39318,39321 **** --- 39343,39347 ---- name: abnormal neural plate morphology def: "any structural anomaly or absence of the flat, thickened layer of ectodermal cells in the neuroectodermal area of the embryo's dorsal surface that develops into the neural tube and neural crest" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:hdene "Howard Dene, Mouse Genome Informatics Curator"] + is_a: MP:0002085 ! abnormal embryonic tissue morphology is_a: MP:0003861 ! abnormal nervous system development *************** *** 39509,39513 **** id: MP:0006009 name: abnormal neuronal migration ! def: "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] is_a: MP:0004811 ! abnormal neuron physiology --- 39535,39539 ---- id: MP:0006009 name: abnormal neuronal migration ! def: "any anomaly in the movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] is_a: MP:0004811 ! abnormal neuron physiology *************** *** 39929,39932 **** --- 39955,39959 ---- id: MP:0006063 name: abnormal inferior vena cava morphology + alt_id: Argent:2810 def: "any structural anomaly of the principal vein draining blood from the lower portion of the body" [ISBN:0-8036-0655-99 "Taber's Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] subset: CvDC_Terms *************** *** 41467,41470 **** --- 41494,41498 ---- def: "abnormality in the mesenchymal cells derived from neural crest cells that contribute to development of the hard and soft tissue in the head and neck, including the branchial arches" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator", PMID:17067568] is_a: MP:0006301 ! abnormal mesenchyme morphology + is_a: MP:0011260 ! abnormal head mesenchyme morphology [Term] *************** *** 46986,46989 **** --- 47014,47018 ---- alt_id: Argent:4508 def: "the development of innumerable cysts in the kidneys filled with fluid replacing much of the mass of the kidneys leading to reduction in kidney function and frequently kidney failure" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] + subset: CvDC_Terms is_a: MP:0003675 ! kidney cysts *************** *** 51172,51176 **** id: MP:0008957 name: abnormal placenta junctional zone morphology ! def: "fetally derived placental region that separates the maternal uterine tissue from the placenta labyrinth" [PMID:16367805] synonym: "abnormal placental junctional zone" EXACT [] synonym: "placenta junctional zone dysplasia" EXACT [] --- 51201,51205 ---- id: MP:0008957 name: abnormal placenta junctional zone morphology ! def: "any structural anomaly of the fetally derived placental region that separates the maternal uterine tissue from the placenta labyrinth" [PMID:16367805] synonym: "abnormal placental junctional zone" EXACT [] synonym: "placenta junctional zone dysplasia" EXACT [] *************** *** 57787,57791 **** id: MP:0009784 name: abnormal melanoblast migration ! def: "defect in the dispersion of the cells that originate from the neural crest and differentiate into pigment cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0002950 ! abnormal neural crest cell migration is_a: MP:0009783 ! abnormal melanoblast morphology --- 57816,57820 ---- id: MP:0009784 name: abnormal melanoblast migration ! def: "any anomaly in the movement of the cells that originate from the neural crest and differentiate into pigment cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0002950 ! abnormal neural crest cell migration is_a: MP:0009783 ! abnormal melanoblast morphology *************** *** 59546,59550 **** id: MP:0009977 name: abnormal cerebellar granule cell migration ! def: "defective or impaired movement of cerebellar granule cell neurons from the germinal zone into the granule cell layer of the cerebellum during development of the cerebellar cortex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0006009 ! abnormal neuronal migration created_by: csmith --- 59575,59579 ---- id: MP:0009977 name: abnormal cerebellar granule cell migration ! def: "any anomaly in the movement of cerebellar granule cell neurons from the germinal zone into the granule cell layer of the cerebellum during development of the cerebellar cortex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0006009 ! abnormal neuronal migration created_by: csmith *************** *** 59846,59850 **** id: MP:0010008 name: abnormal Purkinje cell migration ! def: "defective or impaired movement of immature Purkinje cells from the ventricular zone of the fourth ventricle to the forming Purkinje cell layer during development of the cerebellar cortex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] synonym: "abnormal Purkinje neuron migration" EXACT [] is_a: MP:0006009 ! abnormal neuronal migration --- 59875,59879 ---- id: MP:0010008 name: abnormal Purkinje cell migration ! def: "any anomaly in the movement of immature Purkinje cells from the ventricular zone of the fourth ventricle to the forming Purkinje cell layer during development of the cerebellar cortex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] synonym: "abnormal Purkinje neuron migration" EXACT [] is_a: MP:0006009 ! abnormal neuronal migration *************** *** 63856,63859 **** --- 63885,63889 ---- id: MP:0010406 name: absent atrial septum + alt_id: Argent:1140 def: "absence of the thin membranous structure between the two heart atria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] subset: CvDC_Terms *************** *** 63937,63940 **** --- 63967,63971 ---- id: MP:0010413 name: complete atrioventricular septal defect + alt_id: Argent:1120 def: "a type of atrioventricular septal defect in which a single atrioventricular valve annulus, a common atrioventricular valve, and a defect of the inlet ventricular septum are observed; deficiency of the atrioventricular septum also results in the presence of a large primum atrial septal defect" [http://emedicine.medscape.com] subset: CvDC_Terms *************** *** 63943,63946 **** --- 63974,63978 ---- synonym: "complete AVC" EXACT [] synonym: "complete AVSD" EXACT [] + synonym: "complete common atrioventricular canal" EXACT [] synonym: "complete common AV canal" EXACT [] synonym: "complete ECD" EXACT [] *************** *** 64012,64015 **** --- 64044,64048 ---- id: MP:0010418 name: perimembraneous ventricular septal defect + alt_id: Argent:1310 def: "abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com] subset: CvDC_Terms *************** *** 64022,64025 **** --- 64055,64059 ---- synonym: "perimembranous muscular ventricular septal defect" NARROW [] synonym: "perimembranous outlet ventricular septal defect" NARROW [] + synonym: "ventricular septal defect, membranous" EXACT [] synonym: "VSD, Type 2" EXACT [] is_a: MP:0008823 ! abnormal interventricular septum membranous part morphology *************** *** 64048,64055 **** --- 64082,64091 ---- id: MP:0010420 name: muscular ventricular septal defect + alt_id: Argent:1320 def: "abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com] subset: CvDC_Terms synonym: "Swiss-cheese septum" EXACT [] synonym: "trabecular ventricular septal defect" EXACT [] + synonym: "ventricular septal defect, muscular" EXACT [] synonym: "VSD, Type 4" EXACT [] is_a: MP:0010402 ! ventricular septal defect *************** *** 65951,65956 **** --- 65987,65995 ---- id: MP:0010607 name: common atrioventricular valve + alt_id: Argent:1170 def: "the presence of a single atrioventricular valve instead of both a mitral and tricuspid valve, most commonly due to incomplete or failure of fetal atrioventricular canal septation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + subset: CvDC_Terms synonym: "AVSD AV valvar abnormality" BROAD [] + synonym: "common AV valve" EXACT [] is_a: MP:0002745 ! abnormal atrioventricular valve morphology created_by: csmith *************** *** 69899,69903 **** id: MP:0010984 name: abnormal metanephric mesenchyme morphology ! def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing metanephros; interactions between the ureteric bud and the metanephric mesenchyme leads to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:19828308] synonym: "abnormal metanephric blastema morphology" EXACT [] synonym: "abnormal metanephric mesoderm morphology" EXACT [] --- 69938,69942 ---- id: MP:0010984 name: abnormal metanephric mesenchyme morphology ! def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing metanephros; interactions between the ureteric bud and the metanephric mesenchyme leads to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:19828308] synonym: "abnormal metanephric blastema morphology" EXACT [] synonym: "abnormal metanephric mesoderm morphology" EXACT [] *************** *** 69910,69914 **** id: MP:0010985 name: abnormal kidney mesenchyme morphology ! def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing kidney" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0000527 ! abnormal kidney development created_by: csmith --- 69949,69953 ---- id: MP:0010985 name: abnormal kidney mesenchyme morphology ! def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing kidney" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0000527 ! abnormal kidney development created_by: csmith *************** *** 69918,69922 **** id: MP:0010986 name: abnormal mesonephric mesenchyme morphology ! def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing mesonephros" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0010985 ! abnormal kidney mesenchyme morphology created_by: csmith --- 69957,69961 ---- id: MP:0010986 name: abnormal mesonephric mesenchyme morphology ! def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing mesonephros" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0010985 ! abnormal kidney mesenchyme morphology created_by: csmith *************** *** 69926,69930 **** id: MP:0010987 name: abnormal nephrogenic mesenchyme morphogenesis ! def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing nephron" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0010985 ! abnormal kidney mesenchyme morphology created_by: csmith --- 69965,69969 ---- id: MP:0010987 name: abnormal nephrogenic mesenchyme morphogenesis ! def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing nephron" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] is_a: MP:0010985 ! abnormal kidney mesenchyme morphology created_by: csmith *************** *** 72394,72397 **** --- 72433,72686 ---- creation_date: 2011-07-27T03:43:10Z + [Term] + id: MP:0011249 + name: abdominal situs inversus + alt_id: Argent:3816 + def: "lateral transposition or mirroring of the viscera of the abdomen, sometimes incomplete, with all organs maintaining the normal relative position with respect to each other" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + subset: CvDC_Terms + is_a: MP:0004133 ! heterotaxia + created_by: csmith + creation_date: 2011-09-09T10:53:02Z + + [Term] + id: MP:0011250 + name: abdominal situs ambiguus + alt_id: Argent:3817 + def: "an abnormality in which the abdominal organs are positioned in such a way with respect to each other and the left-right axis as to be not clearly lateralised and thus have neither the usual, or normal (situs solitus), nor the mirror-imaged (situs inversus) arrangements" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:18039396] + subset: CvDC_Terms + synonym: "abdominal heterotaxy" EXACT [] + synonym: "abdominal situs ambiguous" EXACT [] + is_a: MP:0004133 ! heterotaxia + created_by: csmith + creation_date: 2011-09-09T11:26:30Z + + [Term] + id: MP:0011251 + name: bronchial situs inversus + alt_id: Argent:4237 + def: "anomaly in the asymmetry of the bronchi of the lung such that these structures on both the left and right side have the morphology normally seen on the opposite side of the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + subset: CvDC_Terms + is_a: MP:0010854 ! lung situs inversus + created_by: csmith + creation_date: 2011-09-09T11:29:01Z + + [Term] + id: MP:0011252 + name: situs inversus totalis + alt_id: Argent:100 + def: "the complete right to left reversal (transposition) of the thoracic and abdominal organs, including the heart (dextrocardia)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + subset: CvDC_Terms + synonym: "situs inversus with dextrocardia" EXACT [] + is_a: MP:0002766 ! situs inversus + created_by: csmith + creation_date: 2011-09-09T11:31:07Z + + [Term] + id: MP:0011253 + name: situs inversus with levocardia + alt_id: Argent:102 + def: "situs inversus of thoracic and abdominal viscera with the heart remaining normally situated on the left; usually associated with congenital cardiac abnormalities such as transposition of the great vessels and/or spleen defects including asplenia or polysplenia" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + comment: The term "levocardia" can also be used to indicate the absence of dextrocardia, and thus normal positioning of the heart, part of situs solitus, normal positioning of the organs. However, this usage is less frequent. + subset: CvDC_Terms + synonym: "levocardia" BROAD [] + xref: MPATH:714 + is_a: MP:0002766 ! situs inversus + created_by: csmith + creation_date: 2011-09-09T11:36:01Z + + [Term] + id: MP:0011254 + name: superior-inferior ventricles + alt_id: Argent:184 + def: "an abnormality in which the heart ventricles are in a superior-inferior relationship due to abnormal displacement of the ventricular mass along the horizontal plane of its long axis; this frequently occurs together with criss-cross atrio-ventricular relationships" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + subset: CvDC_Terms + synonym: "over-and-under ventricles" EXACT [] + synonym: "supero-inferior heart" EXACT [] + synonym: "upstairs-downstairs heart" EXACT [] + is_a: MP:0005294 ! abnormal heart ventricle morphology + is_a: MP:0006065 ! abnormal heart position or orientation + created_by: csmith + creation_date: 2011-09-09T12:00:47Z + + [Term] + id: MP:0011255 + name: abnormal anterior visceral endoderm cell migration + def: "any anomaly in the movement of the cells of the extraembryonic tissue that is responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate patterning of adjacent embryonic tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:17078044] + synonym: "abnormal AVE cell migration" EXACT [] + is_a: MP:0004264 ! abnormal extraembryonic tissue physiology + created_by: csmith + creation_date: 2011-09-12T02:42:33Z + + [Term] + id: MP:0011256 + name: abnormal neural fold morphology + def: "any structural anomaly of the elevated margins of the neural groove" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"] + synonym: "abnormal medullary fold morphology" EXACT [] + is_a: MP:0002085 ! abnormal embryonic tissue morphology + created_by: csmith + creation_date: 2011-09-12T03:41:17Z + + [Term] + id: MP:0011257 + name: abnormal head fold morphology + def: "any structural anomaly of the crescent-shaped, ventrally located fold of the embryonic disc at the future cephalic end of the developing embryo" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"] + comment: Head fold is properly used to describe the rostrally located, crescent shaped fold of the embryonic disc around the future foregut. However, it is often (and incorrectly) used as a synonym for the ventrally located cephalic neural folds. Take care to select the correct term. + is_a: MP:0002085 ! abnormal embryonic tissue morphology + created_by: csmith + creation_date: 2011-09-12T03:49:42Z + + [Term] + id: MP:0011258 + name: abnormal tail fold morphology + def: "any structural anomaly of the crescent-shaped, ventrally located fold of the embryonic disc at the future caudal end of the developing embryo" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"] + synonym: "abnormal caudal fold morphology" EXACT [] + is_a: MP:0002085 ! abnormal embryonic tissue morphology + created_by: csmith + creation_date: 2011-09-12T03:49:57Z + + [Term] + id: MP:0011259 + name: abnormal cephalic neural fold morphology + def: "any structural anomaly of the elevated margins of the neural groove that are located in the future cephalic region of the embryo" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + comment: Head fold is properly used to describe the rostrally located, crescent shaped fold of the embryonic disc around the future foregut. However, it is often (and incorrectly) used as a synonym for the ventrally located cephalic neural folds. Take care to select the correct term. + synonym: "abnormal head fold morphology" BROAD [] + is_a: MP:0011256 ! abnormal neural fold morphology + created_by: csmith + creation_date: 2011-09-12T04:05:08Z + + [Term] + id: MP:0011260 + name: abnormal head mesenchyme morphology + def: "any structural abnormality in the primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"] + synonym: "abnormal cephalic mesenchyme morphology" EXACT [] + is_a: MP:0002085 ! abnormal embryonic tissue morphology + is_a: MP:0003935 ! abnormal craniofacial development + created_by: csmith + creation_date: 2011-09-13T11:23:04Z + + [Term] + id: MP:0011261 + name: abnormal limb mesenchyme morphology + def: "any structural abnormality in the primordial embryonic connective tissue of the developing limbs, autopods and digits, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to limb connective tissue, bone and musculature in conjunction with myotome cells" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + synonym: "abnormal limb bud mesenchyme" EXACT [] + is_a: MP:0005650 ! abnormal limb bud morphology + created_by: csmith + creation_date: 2011-09-13T11:41:26Z + + [Term] + id: MP:0011262 + name: abnormal branchial arch mesenchyme morphology + def: "any structural abnormality in the primordial embryonic connective tissue associated with the branchial arches, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to facial and cranial nerve-associated structures" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + synonym: "abnormal pharyngeal arch mesenchyme morphology" EXACT [] + is_a: MP:0010395 ! abnormal branchial arch development + is_a: MP:0011260 ! abnormal head mesenchyme morphology + created_by: csmith + creation_date: 2011-09-13T11:46:26Z + + [Term] + id: MP:0011263 + name: abnormal spleen mesenchyme morphology + def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + is_a: MP:0009323 ! abnormal spleen development + created_by: csmith + creation_date: 2011-09-13T12:15:12Z + + [Term] + id: MP:0011264 + name: abnormal cardiac mesenchyme morphology + def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + is_a: MP:0002925 ! abnormal cardiovascular development + created_by: csmith + creation_date: 2011-09-13T12:38:32Z + + [Term] + id: MP:0011265 + name: abnormal pancreas mesenchyme morphology + def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing pancreas" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + is_a: MP:0003934 ! abnormal pancreas development + created_by: csmith + creation_date: 2011-09-13T12:41:20Z + + [Term] + id: MP:0011266 + name: abnormal frontonasal mesenchyme morphology + def: "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the frontonasal region of the head" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + synonym: "abnormal fronto-nasal mesenchyme morphology" EXACT [] + synonym: "abnormal naso-frontal mesenchyme morphology" EXACT [] + is_a: MP:0011260 ! abnormal head mesenchyme morphology + created_by: csmith + creation_date: 2011-09-13T12:45:23Z + + [Term] + id: MP:0011267 + name: abnormal excitatory postsynaptic current amplitude + def: "anomaly in the size (height or maximum displacement) or shape of the evoked excitatory postsynaptic current wave" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + is_a: MP:0002910 ! abnormal excitatory postsynaptic currents + created_by: csmith + creation_date: 2011-09-13T01:39:03Z + + [Term] + id: MP:0011268 + name: biphasic excitatory postsynaptic current amplitude + def: "the appearance of two peaks instead of one peak in the evoked excitatory postsynaptic current wave" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + is_a: MP:0011267 ! abnormal excitatory postsynaptic current amplitude + created_by: csmith + creation_date: 2011-09-13T01:39:03Z + + [Term] + id: MP:0011269 + name: increased excitatory postsynaptic current amplitude + def: "increase in the size (height or maximum displacement) of the evoked excitatory postsynaptic current wave" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + is_a: MP:0011267 ! abnormal excitatory postsynaptic current amplitude + created_by: csmith + creation_date: 2011-09-13T01:39:03Z + + [Term] + id: MP:0011270 + name: decreased excitatory postsynaptic current amplitude + def: "reduction in the size (height or maximum displacement) of the evoked excitatory postsynaptic current wave" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + synonym: "reduced excitatory postsynaptic current amplitude" EXACT [] + is_a: MP:0011267 ! abnormal excitatory postsynaptic current amplitude + created_by: csmith + creation_date: 2011-09-13T01:39:03Z + + [Term] + id: MP:0011271 + name: prolonged excitatory postsynaptic current rise time + def: "an increase in the time required for a signal to change from resting to the peak amplitude value in the evoked excitatory postsynaptic current wave" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + is_a: MP:0002910 ! abnormal excitatory postsynaptic currents + created_by: csmith + creation_date: 2011-09-13T01:39:03Z + + [Term] + id: MP:0011272 + name: short excitatory postsynaptic current rise time + def: "an decrease in the time required for a signal to change from resting to the peak amplitude value in the evoked excitatory postsynaptic current wave" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] + is_a: MP:0002910 ! abnormal excitatory postsynaptic currents + created_by: csmith + creation_date: 2011-09-13T01:39:03Z + + [Term] + id: MP:0011273 + name: prolonged excitatory postsynaptic current decay time + is_a: MP:0002910 ! abnormal excitatory postsynaptic currents + created_by: csmith + creation_date: 2011-09-13T01:39:03Z + + [Term] + id: MP:0011274 + name: short excitatory postsynaptic current decay time + is_a: MP:0002910 ! abnormal excitatory postsynaptic currents + created_by: csmith + creation_date: 2011-09-13T01:39:03Z + + [Term] + id: MP:0011275 + name: abnormal behavioral response to light + def: "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] + is_a: MP:0004924 ! abnormal behavior + created_by: csmith + creation_date: 2011-09-13T02:14:19Z + [Typedef] id: part_of |