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I don't see any particular reason why this should be integrated into N++ as a plugin and by the lack of replies I'm guessing that nobody else does either. If you want it integrated you could read the plugin author pages on the wiki and browse the source of another plugin or use the Python Script plugin.
Why not just use the simplest option? N++ has a run feature (Run -> Run... in the menu). Just create a run entry and if you want, bind it to a keyboard shortcut. There are macros you can use like c:\dir\example.exe -a "$(FULL_CURRENT_PATH)".
c:\dir\example.exe -a "$(FULL_CURRENT_PATH)"