The most evident difference and shortcoming of Joe Vs any other editor: it is currently unable to copy/cut and paste text to another arbitrary location, that is, to the clipboard.
Is that really impossible ?
This is not impossible and it is possible to do it even without too much coding. You can use macro language to define it. All you need is a xsel (http://www.niksula.hut.fi/~vherva/xsel/). This is quite small application that can work with X's clipboard. JOE is not dependent on X libraries so it cannot have access to this clipboard.
Another way is to use joe with a recent version of xterm compiled with the paste64 option. Enable the -joexterm and -mouse options in joe and text selected with the mouse ends up on the clipboard.