#9908 TPV: spindle pole body

closed-fixed
None
5
2012-12-19
2012-12-19
Valerie Wood
No

The term spindle pole body has a parentage to cytoplasmic part which is not true for organisms which undergo a closed mitosis.
i guess the parent microtubule organizing centre needs the "cytoplasmic part" parent removing?.. but its def says "cytoplasmic part", that is probably causing the reasoner to suggest this relationship ...the def needs refining...

val

Discussion

    • assigned_to: nobody --> paolaroncaglia
     
  • Hi Val,

    How about editing the def. to:

    An *intracellular* structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides. It may be associated with the nuclear envelope and, occasionally, also be found free in the cytoplasm.
    PMID: 17072892
    http://en.wikipedia.org/wiki/Microtubule_organizing_center
    GOC:vw

    and I'd remove the 'cytoplasmic part' parent.
    Thanks,
    Paola

     
  • Valerie Wood
    Valerie Wood
    2012-12-19

    I would not say "It may be associated with the nuclear
    envelope and, occasionally, also be found free in the cytoplasm"

    As it is largely cytoplasmic in higher eukaryotes with open mitosis.
    I think I would just leave out this part...
    val

     
  • Thanks Val, this is fixed now.
    Current stanza is:

    id: GO:0005815
    name: microtubule organizing center
    namespace: cellular_component
    def: "An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides." [GOC:vw, http://en.wikipedia.org/wiki/Microtubule_organizing_center, ISBN:0815316194, PMID:17072892, PMID:17245416]
    subset: goslim_candida
    subset: goslim_generic
    subset: goslim_yeast
    synonym: "microtubule organising centre" EXACT []
    synonym: "MTOC" EXACT []
    xref: Wikipedia:Microtubule_organizing_center
    is_a: GO:0044430 ! cytoskeletal part
    relationship: part_of GO:0015630 ! microtubule cytoskeleton

    Cheers,
    Paola

     
    • status: open --> closed-fixed