I am annotating some ANK proteins and I think they would benefit from having ion channel localization as a GO term. PMID:15178757 identifies that ANK2 in mouse and human affect the localization of Na/Ca exchanger, Na/K ATPase, and inositol trisphosphate (InsP(3)) receptor to transverse-tubule/sarcoplasmic reticulum sites in cardiomyocytes. Whereas downregulation of ANK3 prevents correct plasma membrane localisation of Sodium channels PMID:18180363, PMID:17620337.
So possible terms:
GO:0072659 protein localization in plasma membrane
>is_a child ion channel localization in plasma membrane
GO:0070972 protein localization in endoplasmic reticulum
>is_a child protein localization in sarcoplasmic reticulum
>>is_a child ion channel localization in sarcoplasmic reticulum
>>is_a child receptor localization in sarcoplasmic reticulum
What do you think?