All versions of Burn I've tried will crash when burning a .bin/.cue if the file extension is uppercase, i.e. .BIN rather than .bin. I've tried Burn 1.7, 2.3, and 2.4.1, all with the same results: as soon as I tell the CD to burn, it hangs for a few seconds at "Preparing data...", and then the app crashes.
A workaround for now is to change the extension to .bin (lowercase) and to edit the .cue file to match.
Note that Burn also crashes, in much the same way, if the .cue file contains an incorrect path; that needs a fix too.
This is on a PowerBook G4/1.67GHz running OS X 10.4.11 with 2 GB RAM.