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Immunocompromised patients are the most likely to gain from enhanced
bactericidal activity possibly offered by lactam-aminoglycoside combination
therapy.9 In a comparison of lactam monotherapy with lactam-aminoglycoside
combination therapy restricted to patients with neutropenia we found no
advantage to combination treatment.89 Although the approach to the
management of patients with and without neutropenia is separated in clinical
practice, this similarity supports a biological basis underlying our
results.
But the villagers had now decided that the boy was their enemy, and no
sooner had he touched the ground than a shower of stones and sticks rained
about him
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